CABG vs Stents for Diabetics: What the Evidence Says

Rahul R. Handa, MD
September 19, 2025
#blog
Image comparing CABG vs Stent

Introduction

When someone with diabetes develops blocked heart arteries, doctors often consider two main treatments: coronary artery bypass grafting (CABG) or stents (also called PCI, or percutaneous coronary intervention). Both restore blood flow, but decades of research show that outcomes differ significantly for people with diabetes. This article explains what the evidence says, why bypass surgery often has better long-term results, and what families should know when facing this decision.

Why Diabetes Changes the Picture

Diabetes affects not only blood sugar but also the health of arteries throughout the body. People with diabetes tend to:

  • Have more widespread and severe blockages
  • Experience faster progression of coronary artery disease
  • Face higher risks of complications like heart attack and stroke

Because of this, choosing the right treatment is critical.

What the Evidence Shows

Several major studies have compared CABG with stents in diabetic patients:

  • FREEDOM Trial (2012): Showed that CABG significantly reduced the risk of death and heart attack compared to stents in diabetics with multiple blocked arteries. Stroke risk was slightly higher with CABG.
  • SYNTAX and Other Trials: Confirmed that bypass surgery provides better survival and fewer repeat procedures in diabetics with complex coronary disease.
  • Real-World Registries: Consistently show CABG has more durable results, though recovery is longer.

Key takeaway: For most diabetic patients with more than one blocked artery, CABG offers better long-term survival and fewer repeat interventions than stents.

Risks and Recovery

CABG:

  • Major surgery requiring hospital stay and longer recovery (6–12 weeks)
  • Risks: infection, stroke, atrial fibrillation
  • Benefits: more complete revascularization and durability

Stents (PCI):

  • Less invasive, often same-day or next-day discharge
  • Faster recovery, but higher chance of needing repeat procedures
  • Risks: stent re-narrowing, need for long-term blood thinners

Special Considerations for Families

Patient health: Frailty, kidney disease, or lung problems may make surgery riskier.

Artery anatomy: The number and location of blockages influence which option is best.

Patient preference: Some patients prioritize avoiding surgery, others value long-term durability.

The Bottom Line

For many diabetic patients with multivessel coronary artery disease, bypass surgery (CABG) offers a survival advantage over stents. However, the decision is never one-size-fits-all. It requires a careful discussion between the heart team - surgeons, cardiologists, and the patient’s family.

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If you or a loved one with diabetes is facing this choice, make sure you ask for a full explanation of both options. At Verus, we provide patients and families with clear, evidence-based reports to guide these critical decisions.

Schedule a complimentary 30-minute call with a cardiac surgeon.

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